Stanford University

Center for Marfan Syndrome

and Related Aortic Disorders 

           


History and Mission

The Stanford University Marfan Clinic was established in 1988 by Dr. D. Craig Miller at the urging of the local chapter of the National Marfan Foundation based upon the perceived need to establish a specialized care center in the western United States. To reflect the broader mission of the Center our name has changed to The Stanford University Center for Marfan Syndrome and Related Aortic Disorders.

Marfan syndrome was initially described in 1896 and is now recognized as a genetic disorder of connective tissue that affects the bones, joints, eyes, blood vessels and the heart. Recent studies in molecular genetics have identified the fibrillin gene product as the defective connective tissue protein that causes Marfan syndrome. Marfan syndrome affects approximately 1 per 5,000 individuals throughout the world including both genders as well as all races and ethnic groups. Prior to innovations in the medical and surgical management of this disease, most patients died of cardiovascular complications by the age of 50.

The central mission of the Stanford University Center for Marfan Syndrome and Related Aortic Disorders is to be an integrated, multi-disciplinary unit that provides comprehensive, cost-effective, state-of-the-art diagnostic evaluation and care for adult and pediatric patients with Marfan syndrome and related aortic disorders including familial aortic disease and bicuspid aortic valve disease. Our ultimate goal is to enable our patients to live long productive and fulfilling lives despite the limitations of these genetic disorders. Toward that goal, the members of the center are working to understand how the type of mutation affects the clinical manifestations of Marfan syndrome, familial aortic disease and bicuspid aortic valve disease and on new surgical options such as valve sparing aortic root replacement surgery.


Staff of The Stanford University Center for Marfan Syndrome and Related Aortic Disorders


Some Questions and Answers about the Center


Other Resources

National Marfan Foundation
22 Manhasset Avenue
Port Washington, NY 11050-9801
1-800-8-MARFAN ext 10 (1-800-862-7326)
1-516-883-8712
Fax: 1-516-883-8040
e-mail: staff@marfan.org

Northern California Chapter of the National Marfan Foundation
3919 Blackstone Court,
Hayward, CA 94542
Phone: (510)982-0246


The logo at the top of the left of this page was adapted from original artwork by Susan Imhoff.

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